Nico Andriesse was born on 18 March 1914 in Roermond. He was the eldest son of Henri Andriesse and Annatje Andriesse-Bouman. The couple had two other sons: Bernard and Alfred. His father, Henri, was a butcher by profession.
Nico worked as a sales representative for the Zwanenberg company in Oss, a slaughterhouse and meat-processing firm. For several years, he lived in rented accommodation in Amersfoort at Sint Anfridusstraat 49.
In 1934, he moved from The Hague to Eindhoven. In 1941, Nico Andriesse was living with his parents at Hoogstraat 47a in Eindhoven. His father offered Jewish travelling salesmen, who were no longer welcome at other addresses, the opportunity to come to his home for a sandwich and coffee or tea.
After 1941, until his deportation, Nico lived at Emmastraat 18a in Enschede. He was deported from Westerbork on 31 August 1942. Nico Andriesse was murdered in Central Europe on 28 February 1943.
His parents and brothers survived the war. Bernard married Rachel Olman in 1942; she also lived at Hoogstraat 47a. Bernard and Rachel worked in the Philips-Kommando.
Alfred and his parents went into hiding.